Stable nanoemulsions self-assembly in nature and nanomedicine / [electronic resource] :

• 作者： D'Arrigo, Joseph S.
• 其他題名：
  • Studies in interface science,
• 出版： Amsterdam : Elsevier
• 叢書名： Studies in interface science,25
• 主題： Emulsions , Emulsions (Pharmacy) , Nanomedicine. , TECHNOLOGY & ENGINEERING--Chemical & Biochemical. , SCIENCE--Chemistry--Industrial & Technical. , Electronic books.
• ISBN： 9780444538451 (electronic bk.) 、 0444538453 (electronic bk.)
• FIND@SFXID: CGU
• 資料類型: 電子書
• 內容註: Includes bibliographical references (p. 343-409) and index. Part I. Natural Coated Microbubbles in the Biosphere -- Part II. Physicochemical Properties of Natural Microbubble Surfactant -- Part III. Physicochemical Properties of Artificial Coated Microbubbles and Nanoparticles -- Part IV. Lipid-Coated Microbubbles and Related Lipid Nanoparticles in Biomedical Studies on Animals -- Part V. Self-Assembling Mixed-Lipid Microbubbles and Nanoparticles for Clinical Applications -- Part VI. "LCM/Nanoparticle-Derived" Nanoemulsions: Biological Lipid Polymorphism, and Receptor Mediated Endocytosis, used for Clinical Study.
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• 摘要註: Certain stable lipid nanoemulsions, existing in natural waters and certain artificial media, display - upon intravenous injection - a marked capability for rapid active targeting, both to tumors and to certain lesion sites. This category of lipid nanoemulsions contains no phospholipids, no proteins nor peptides, no carbohydrates, and no chemical modification of the lipophilic drugs is required; consequently it avoids various past problems reported for earlier versions of targeted nanoemulsions. The book covers in detail the underlying chemical and biochemical principles of stable lipid nanoemulsions as well as many current and potential applications in nanomedicine such as targeted chemotherapy. It is in harmony with goals of the current US National Nanotechnology Initiative, which include nanomedical approaches to drug delivery that focus on developing nanoscale particles to improve drug bioavailability i.e. often using targeted nanoparticles for delivering drugs with cell precision and less side effects. Despite the obvious practical importance to various fields including nanomedicine there is currently no comprehensive book available in the literature. The proposed book will effectively fill this gap. Detailed coverage of the underlying chemical and biochemical principles of stable lipid nanoemulsions. The book includes many current and potential applications in nanomedicine such as targeted chemotherapy. Contains 67 figures (including 13 microscope photos) and 26 tables Over 1200 literature references, many of them of very recent date.
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