High-performance algorithms for mass spectrometry-based omics [electronic resource]
- 作者： Saeed, Fahad.
- 其他作者：
- 其他題名：
- Computational biology.
- 出版： Cham : Springer International Publishing :Imprint: Springer
- 叢書名： Computational biology,
- 主題： Mass spectrometry--Data processing. , High performance computing. , Computer algorithms. , Computational and Systems Biology. , Mass Spectrometry. , Theory and Algorithms for Application Domains. , Computer Science.
- ISBN： 9783031019609 (electronic bk.) 、 9783031019593 (paper)
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FIND@SFXID:
CGU
- 資料類型: 電子書
- 內容註: 1. Need for High Performance Computing for Big MS Data -- 2. Introduction to Mass Spectrometry Data -- 3. A Review of Spectral Pre-processing -- 4. MS-REDUCE: An Ultra Data Reduction Algorithm -- 5. GPU-DAEMON: A Template to Support Development of GPU Algorithms -- 6. GPU-ArraySort: GPU Based Array Sorting Technique -- 7. G-MSR: A GPU Based Dimensionality Reduction Algorithm -- 8. Simulator Driven Proteomics -- 9. Future and Proposed Work.
- 摘要註: To date, processing of high-throughput Mass Spectrometry (MS) data is accomplished using serial algorithms. Developing new methods to process MS data is an active area of research but there is no single strategy that focuses on scalability of MS based methods. Mass spectrometry is a diverse and versatile technology for high-throughput functional characterization of proteins, small molecules and metabolites in complex biological mixtures. In the recent years the technology has rapidly evolved and is now capable of generating increasingly large (multiple tera-bytes per experiment) and complex (multiple species/microbiome/high-dimensional) data sets. This rapid advance in MS instrumentation must be matched by equally fast and rapid evolution of scalable methods developed for analysis of these complex data sets. Ideally, the new methods should leverage the rich heterogeneous computational resources available in a ubiquitous fashion in the form of multicore, manycore, CPU-GPU, CPU-FPGA, and IntelPhi architectures. The absence of these high-performance computing algorithms now hinders scientific advancements for mass spectrometry research. In this book we illustrate the need for high-performance computing algorithms for MS based proteomics, and proteogenomics and showcase our progress in developing these high-performance algorithms.
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讀者標籤：
- 系統號： 005516792 | 機讀編目格式
館藏資訊
To date, processing of high-throughput Mass Spectrometry (MS) data is accomplished using serial algorithms. Developing new methods to process MS data is an active area of research but there is no single strategy that focuses on scalability of MS based methods. Mass spectrometry is a diverse and versatile technology for high-throughput functional characterization of proteins, small molecules and metabolites in complex biological mixtures. In the recent years the technology has rapidly evolved and is now capable of generating increasingly large (multiple tera-bytes per experiment) and complex (multiple species/microbiome/high-dimensional) data sets. This rapid advance in MS instrumentation must be matched by equally fast and rapid evolution of scalable methods developed for analysis of these complex data sets. Ideally, the new methods should leverage the rich heterogeneous computational resources available in a ubiquitous fashion in the form of multicore, manycore, CPU-GPU, CPU-FPGA, and IntelPhi architectures. The absence of these high-performance computing algorithms now hinders scientific advancements for mass spectrometry research. In this book we illustrate the need for high-performance computing algorithms for MS based proteomics, and proteogenomics and showcase our progress in developing these high-performance algorithms.